DOT physicals in South Carolina

The FMCSA National Registry lists 837 certified medical examiners accepting exams at 501 locations in South Carolina. The most are in Columbia (93), Greenville (76) and North Charleston (43).

Interstate vs. in-state driving. The federal DOT physical rules apply to interstate commercial drivers. South Carolina may apply its own medical rules to drivers who stay inside the state; check with the South Carolina driver licensing agency. After June 23, 2025, examiners send CDL and CLP exam results to state licensing agencies through the National Registry. How that works.

Cities in South Carolina

Other locations in South Carolina

Abbeville

Andrews

Ballentine

Batesburg

Blacksburg

Blackville

Blythewood

Calhoun Falls

Central

Charlotte

Clinton

Clover

Due West

Edgefield

Fairfax

Fountain Inn

Great Falls

Greenvilee

Hilton Head Island

Holly Hill

Honea Path

Iva

Jefferson

Lake View

Landrum

Laurens

Leesville

Little River

Marion

Morganton

Mullins

Okatie

Pacolet

Peak

Pelzer

Pendleton

Piedmont

Prosperity

Richburg

Roebuck

Saluda

Santee

Scranton

Sharon

Summerton

Swansea

Varnville

Williamston

Registry data checked November 11, 2026 · Source: FMCSA National Registry